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    dcyphr-d by Akaash Saraf on 2020-06-18
    Abstract:A certain chemical family known as flavonoids activate pathways that combat oxidative stress. Oxidative stress is the phenomenon in which an imbalance in oxidants and antioxidants leads to programmed cell death. The pathways that are activated are the hypoxia inducible factor (HIF) and Nrf2. It is important to note that not all flavonoids are activators of these two pathways. NDGA, a chemical similar to flavonoids, was chosen in this study due to its strong ability to activate the Nrf2 ...
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    dcyphr-d by Oby Uche on 2020-06-18
    Abstract Tree growth was investigated in Isle Royale National Park in Michigan to reveal the influence of herbivores and carnivores on plants in an intimately linked food chain. Plant growth rates were regulated by the amount of certain types of animals present (moose and wolves), and the plants only responded to annual changes in primary productivity when they were no longer under pressure from moose. The study revealed top-down control in the Isle Royale ecosystem.Background The top-down...
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    dcyphr-d by Janet Hsu on 2020-06-18
    AbstractThe jellyfish Aequorea victoria expresses green fluorescent protein (GFP). A complementary DNA can be expressed in prokaryotic or eukaryotic cells. Other substrates or cofactors are not necessary for this fluorescence. Thus, GFP can be used to monitor gene expression and protein localization in living organisms.IntroductionIn the jellyfish Aequorea victoria, the green fluorescent protein (GFP) emits a green light. When the photoprotein aequorin binds to calcium, GFP absorbs excitation en...
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    dcyphr-d by Leanna Zelle on 2020-06-18
    AbstractVessel formation (angiogenesis) and inflammation are closely related. A protein on the vessel cells called Endoglin (CD105) is involved in angiogenesis. So this study aims to see if CD105 is also involved in inflammation. They used antibody staining to look at CD105 levels during inflammation and angiogenesis. CD105 was found in low levels in most of the tissue throughout the body. But, it was found at high levels in capillaries near hair follicles, alveoli, and lymph nodes. During wound...
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    dcyphr-d by Leanna Zelle on 2020-06-18
    AbstractThis goal of this study is to see if levels of Vitamin D affects case rate and mortality rate of COVID-19 in European countries. It was found that with higher levels of Vitamin D, the case rate and mortality rate were lower.BackgroundIn many other respiratory tract infections, Vitamin D helps to prevent more serious complications. But COVID-19 may be different because the virus interacts with ACE2 to enter the cell. Calcitriol, which is a form of Vitamin D, increases the amount of ACE2. ...
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    dcyphr-d by Daniel Amuedo on 2020-06-18
    Abstract     Studies show that microplastic has a negative impact on the wildlife. Thus the presence of microplastic in marine species that humans consume presents a health risk to humans. This study reviews the potential health effects of microplastic in marine species on human food security and human health. Knowledge on this subject is very limited and this study pushes the boundary of our knowledge. Additional research in this area is needed to ensure human health and food security. Backgrou...
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    dcyphr-d by Janet Hsu on 2020-06-18
    AbstractThe relationship between biodiversity and latitude is controversial. Research that includes immigration and not just origin or extinction support the “out of the tropics” model. This model indicates that taxa prefer to originate from the tropics. Then, they migrate to the poles while remaining in the tropics. Thus, the tropics are a cradle and a museum.IntroductionThe latitudinal diversity gradient (LDG) is the phenomenon that as one moves from the poles to the equator (tropics), there i...
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    dcyphr-d by Daniel Amuedo on 2020-06-18
    AbstractSince SARS-CoV-2 is thought to have originated from bats, it is of significant importance that we observe the susceptibility of other animals as a potential transmission route. In this study the researchers investigate how susceptible ferrets and other animals that are in close contact with humans are to SARS-CoV-2. The researchers found that SARS-CoV-2 replicates poorly in dogs, pigs, chickens, and ducks. However ferrets and cats are not as resistant to infection as the other animals st...
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    dcyphr-d by Janet Hsu on 2020-06-18
    AbstractThe three proteins, Sar1p, Sec13p complex, and Sec23p complex, contribute to the synthesis of transport vesicles. The vesicles derive from the endoplasmic reticulum. Vesicle formation requires GTP. But, GMP-PNP, a nonhydrolyzable analog of GTP, can cause vesicle formation as well. But, GMP-PNP vesicles cannot target and fuse with the Golgi complex. All three proteins remain on the vesicles. Yet, GTP vesicles are functional. Sar1p dissociates from GTP vesicles, allowing for fusion. Thin s...
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    dcyphr-d by Daniel Amuedo on 2020-06-18
    Abstract In cell samples grown in a laboratory setting, the antiparasitic medication ivermectin has shown to be effective against SARS-CoV-2. This has peaked interest because it could possibly treat COVID-19. This study looks at the feasibility of ivermectin as a treatment for COVID-19. The dose needed to be effective against COVID-19 is likely too high for humans to use safely. Introduction As the COVID-19 pandemic continues, several possible drugs are being explored as a tre...